Fiber to combat antibiotic resistance
Antibiotic-resistant microbes are a huge problem around the world, one that is likely to get worse in the coming decades. However, proper nutrition could help combat this threat. One varied diet with enough Soluble fiber reduces antibiotic-resistant microbes in the gut.
In a new study involving experts from US Department of Agriculture—Agricultural Research Service (ARS) found that healthy people who eat a varied diet and consume at least eight to ten grams of soluble fiber per day fewer antibiotic-resistant bacteria they have in their intestines.
The results were published in the English journal “mBio”.
Increased resistance to antibiotics
According to that Robert Koch Institute (RKI), each use of antibiotics promotes the development of resistance by killing sensitive bacteria and allowing more resistant bacteria to survive and continue to multiply.
If an antibiotic loses its effect, this is associated with the fact that resistant pathogens are often more difficult to treat, which means that harmless infections become one. more complicated course can take, which can ultimately even end in the death of the person in question.
The biggest challenge for global health
The emergence of resistance to antibiotics. not preventedbut at most slow down, so they continue to increase globally. According to the RKI, antibiotic resistance is one of the biggest global health challenges today.
Role of the gut microbiome in antibiotic resistance
Antimicrobial resistance in humans is largely due to gut microbiome attributed. The microbes found there carry genetically encoded strategies that allow them to survive contact with antibioticsthe researchers report.
Diet changes against antibiotic resistance
Due to the great influence of the food consumed in the composition of the intestinal microbiome, a change in diet According to the researchers, they represent an effective weapon in the fight against antibiotic resistance.
“This is not an exotic diet, but a varied and high-fiber diet, as some Americans already eat.‘, explains the author of the study. Danielle Lemay from the Agricultural Research Service in a press release.
Antibiotic resistance genes due to poor diet?
Therefore, the researchers attempted specific relationships between the salary of antibiotic resistance genes in human gut microbes and fiber and animal protein in the diet of adults.
More fiber and less protein
It turned out that regular consumption of a highest fiber Y low protein Foods, especially beef and pork, were significantly correlated with lower levels of antimicrobial resistance genes (ARGs) in gut microbes.
Anaerobic Microbes Indicate a Healthy Gut
People with the lowest levels of these genes in their gut microbiome also had higher numbers strictly anaerobic microbes up, so the team. These are bacteria that do not thrive in the presence of oxygen. These bacteria are contracting Signs of a healthy gut with little inflammation.
Experts also report that the amount of animal protein in nutrition, however not an important predictor of high ARG values it was. The strongest association was between higher levels of dietary soluble fiber and lower levels of ARG.
What is soluble fiber?
Soluble fiber dissolve in water, as its name suggests. They are mainly found in cereals such as barley and oats, in legumes such as beans, lentils and peas, and also in seeds and nuts. They are also found in some fruits and vegetables such as carrots, berries, artichokes, and broccoli.
Diversity in diet is very important
“Surprisingly, the most important predictor of low ARG, ahead of fiber, was dietary variety. This suggests that we should eat a diverse diet of foods that tend to be higher in soluble fiber to reap maximum benefit.“, how that lemay.
In addition, the study showed that people who higher ARG values in their gut microbiome, compared to individuals with low and intermediate levels of ARG, significantly less diverse gut microbiome had.
Diet to reduce antibiotic resistance.
“Our diet provides food for gut microbes. All of this suggests that our diet could be a solution to reduce antimicrobial resistance by altering the gut microbiome.“he explained lemay.
The expert adds that nutritional measures could contribute to that global burden of antibiotic resistance to reduce. This could even help create dietary guidelines that take into account how diet can reduce the risk of antibiotic-resistant infections. (What)
Author and source of information
This text corresponds to the specifications of the specialized medical literature, medical guidelines and current studies and has been reviewed by medical professionals.
- Andrew Oliver, Zhengyao Xue, Yirui T. Villanueva, Blythe Durbin-Johnson, Zeynep Alkan, et al: Association of diet and antimicrobial resistance in healthy US adults; In: mBio (published May 10, 2022), mBio
- US Department of Agriculture – Agricultural Research Service: High-Fiber Diets Associated With Less Antibiotic Resistance in Gut Bacteria (Published 05/10/2022), ARS
- Rober Koch Institute: Basic Understanding of Antibiotic Resistance (as of May 9, 2019), RKI
This article contains general advice only and should not be used for self-diagnosis or treatment. It cannot replace a visit to the doctor.