Does dad’s diet make kids sick?

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You are what you eat. Almost everyone knows this saying. But as scientists have now discovered in a new study, the nutrition of men also have a big impact on the health of their daughters. Consequently, not only the mother’s way of life influences the unborn child, but also that of the father.

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An unhealthy diet in men can have fatal consequences

Pregnant women often attach great importance to their current lifestyle. you try to eat healthy move regularly and avoid stress to better protect the fetus. Because it is well known that lifestyle and environmental factors can endanger the health of the embryo.

What is new, however, is the realization that a father’s or even a grandfather’s unhealthy diet can cause harm. According to the Medical Clinic V. of the Mannheim University of Medicine (UMM), the “current animal study provides clear evidence that an unhealthy diet during sperm formation can lead to kidney disease, especially in female offspring.

The international research team published their findings in the specialist journal “The Faseb Journal”.

Scientists hold the cage

For research purposes, the researchers put two generations of male rats on an unhealthy diet. (icon image)

© dpa, Uwe Anspach and others kde

The experiment was carried out on two generations of male rats.

For research purposes, scientists keep male rats for two generations. an unhealthy diet exposed. This contained high concentrations of fats, carbohydrates and salt. They then looked at the effects on the kidney health of the offspring. “To do this, the glomerular filtration rate – the volume filtered by the glomeruli of the kidneys per unit of time – was recorded and the excretion of albumin in the urine was determined. The glomerular filtration rate is one of the most important parameters for evaluate the kidneys, while increased albumin excretion may be an early sign of kidney damage,” according to the researchers.

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Additional studies should show whether the findings can also be transferred to humans.

In the first generation of offspring, both glomerular filtration rate (GFR) and albumin excretion were normal. In female offspring of the second generation, however, the scientists found greater excretion of the protein. And the GFR was significantly reduced. “F2 female offspring developed renal fibrosis and glomerular sclerosis”. in a fibrosis is the scarring of an organ, sclerosis is the hardening of an organ or tissue.

“The animal study actually shows that an unhealthy diet of the father before conception for two generations predisposes the F2 female offspring to the development of chronic kidney disease,” summarizes Prof. Dr. Bernhard Krämer, Director of the Medical Clinic V., summarized the results of the study.

To what extent these findings can be transferred from rats to humans, the scientists want to examine in further studies. (kko)

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